interfereinterfereinterferesinterferedinterferingverb (interferes, interfering, interfered)1to try to do something with or for somebody, when they do not want your help: Don't interfere! Let John decide what he wants to do.2to stop something from being done well: His interest in football often interferes with his studies.▶ interferenceinterferenceinterferencesnoun (no plural): I don't want any interference in my affairs!