twisttwisttwiststwistedtwistingverb (twists, twisting, twisted)1to change the shape of something by turning it in different directions; to turn in many directions: She twisted the metal into strange shapes. The path twists and turns through the forest.2to turn something with your hand: Twist the lid off the jar.3to turn something round another object many times: They twisted the sheets into a rope and escaped through the window.4to hurt part of your body by suddenly turning it in a way that is not natural: She fell and twisted her ankle.▶ twistnoun: the twists and turns of the river She gave the handle a hard twist.